Análisis de la sensibilidad gustativa al estímulo amargo en dos poblaciones mexicanas

Authors

DOI:

https://doi.org/10.29105/idcyta.v9i1.127

Keywords:

Sensibilidad gustativa, Propiltiouracilo, Distribución de frecuencias

Abstract

La sensibilidad gustativa al sabor amargo del propiltiouracilo (PROP) ha sido considerada como un indicador de sensibilidad general a diversos estímulos orales. La intensidad de percepción del PROP permite clasificar a las personas como No Degustadoras (ND), Degustadoras (D) y Superdegustadoras (SD), cuya proporción varía entre poblaciones. En México existen pocos estudios sobre la distribución de estas frecuencias. Por lo tanto, el objetivo de este estudio fue identificar y analizar las proporciones de ND, D y SD en dos poblaciones de la región central del país. Para lograr este propósito se evaluó la sensibilidad a PROP de los participantes (148 en Guanajuato y 163 en Hidalgo), aplicando el método de tres soluciones. La distribución total de frecuencias fue de 50, 204 y 57, correspondiendo con el 16, 66 y 18 % de ND, D y SD, respectivamente. No se observaron diferencias significativas entre poblaciones [ꭓ2(2,0.05) =4.83; P=NS]. Estos resultados difieren de los reportados en poblaciones del norte y el sur de México. Los resultados de este trabajo dan pauta a desarrollar más investigaciones de este tipo en el área de evaluación sensorial en México.

Downloads

Download data is not yet available.

References

Aréchiga-Viramontes & Mejía-Sánchez, M. (2013). Sensibilidad gustativa a la faniltiocarbamida en poblaciones mayas. Estudios de Cultura Maya, 21, 15-24. DOI: https://doi.org/10.19130/iifl.ecm.2000.21.424

Baker, A.N., Miranda, A.M., Garneau, N.L. & Hayes, J.E. (2018). Self-reported smoking status, TAS2R38, variants, and propylthiouracil phenotype: An exploratory crowdsourced cohort study. Chemical Senses, 43, 617-625. DOI: https://doi.org/10.1093/chemse/bjy053

Barajas-Ramírez, J.A., Quintana-Castro, R., Oliart-Ros, R.M. & Angulo-Guerrero, O. (2016). Bitter taste perception and TAS2R38 genotype: effects on taste sensitivity, food consumption and anthropometry in Mexican adults. Flavour and Fragrance Journal, 31(4), 310-318. DOI: https://doi.org/10.1002/ffj.3319

Calò, C., Padiglia, A., Zonza, A., Corrias, L., Contu, P., Tepper, B.J. & Barbarossa, I.T. (2011). Polymorphisms in TAS2R38 and the taste bud trophic factor, gustin gene co-operate in modulating PROP taste phenotype. Physiology & Behavior, 104(5), 1065-1071. DOI: https://doi.org/10.1016/j.physbeh.2011.06.013

Chamoun, E., Hutchinson, J.M., Krystia, O., Mirotta, J.A., Mutch, D.M., Buchholz, A.C., Duncan, A.M., Darlington, G., Haines, J., Ma, D.W.L. & Guelp Family Health Study. (2018). Single Nucleotide Polymorphisms in taste receptor genes are associated with snacking patterns of preschool-aged children in the Guelp Family Health Study: A pilot study. Nutrients, 10, 153. DOI: https://doi.org/10.3390/nu10020153

Choi, S.E. & Chan, J. (2015). Relationship of 6-n-propylthiouracil taste intensity and chili pepper use with body mass index, energy intake, and fat intake within an ethnically diverse population. Journal of the Academy of Nutrition and Dietetics. 115(3), 389-396. DOI: https://doi.org/10.1016/j.jand.2014.09.001

Deshaware, S. & Singhal, R. (2017). Genetic variation in bitter taste receptor gene TAS2R38, PROP taster status and their association with body mass index and food preferences in Indian population. Gene, 627, 363-368. DOI: https://doi.org/10.1016/j.gene.2017.06.047

Diószegi, J., Llanaj, E. & Ádány, R. (2019). Genetic background of taste perception, taste preferences, and its nutritional implication: A systematic review. Frontiers in Genetics, 10, 1272. DOI: https://doi.org/10.3389/fgene.2019.01272

Ebba, S., Abarintos, R. A., Kim, D.G., Tiyouh, M., Stull, J.C., Movalia, A. & Smutzer, G. (2012). The examination of fatty acid taste with edible strips. Physiology and Behavior, 106(5), 579-586. DOI: https://doi.org/10.1016/j.physbeh.2012.04.006

Guo, S.-W. & Reed, D. R. (2001). The genetics of pheniltiocarbamide perception. Annals of Human Biology. 28(2), 111-142. DOI: https://doi.org/10.1080/03014460151056310

Hayes, J. E. & Duffy, V.B. (2007). Revisiting sugar-fat mixtures: Sweetness and creaminess vary with phenotipic markers of oral sensation. Chemical Senses, 32, 225-236. DOI: https://doi.org/10.1093/chemse/bjl050

Hwang, L-D., Breslin, P.A.S. Reed, D.R., Zhu, G., Martin, N.G., & Wright, M.J. (2016). Is the association between sweet and bitter perception due to genetic variation? Chemical Senses, 41, 737-744. DOI: https://doi.org/10.1093/chemse/bjw083

Kalmus, H.; De Garay, A.L.; Rodarte, U.; & Cobo, L. (1964). The frequency of PTC tasting, hard ear wax, colour blindness and other genetical characters in urban and rural Mexican populations. Human Biology. 36(2), 134-145

Kurshed, A.A.M., Vincze, F., Pikó, P., Kósa, Z., Sándor, J., Ádány, R. & Diószegi, J. (2023). Taste preference-related genetic polymorphism modify alcohol consumption behavior of the Hungarian General and Roma populations. Genes, 14, 666. DOI: https://doi.org/10.3390/genes14030666

Lambert, J.D.; VanDusen, S.R.; Cockroft, J.E.; Smith, E.C., Greenwood, D.C. & Cade, J.E. (2019). Bitter taste sensitivity, food intake, and risk of malignant cancer in the UK Women´s Cohort Study. European Journal of Nutrition. 58(5), 2111-2121. DOI: https://doi.org/10.1007/s00394-018-1772-4

Martínez-Ruiz. N.R., Wall-Medrano, A., Jiménez-Castro, J.A., Díaz-López, J.A. & Angulo-Guerrero, O. (2014). Relación entre el fenotipo PROP, el índice de masa corporal, la circunferencia de cintura, la grasa corporal total y el consumo dietario. Nutrición Hospitalaria, 29(1), 173-179.

Melis, M. & Barbarossa, I.T. (2017). Taste perception of sweet, sour, salty, bitter, and umami and changes due to L-arginine suppelementation, as a function of genetic ability to taste 6-n-propyltiouracil. Nutrients, 9, 541. DOI: https://doi.org/10.3390/nu9060541

Melis, M., Mastinu, M., Naciri, L.C., Muroni, P. & Barbarossa, I.T. (2022). Associations between sweet taste sensitivity and polymorphisms (SNPs) in the TAS1R1 and TAS1R3 genes, gender, PROP tastes status, and density of fungiform papillae in a genetic homogeneous Sardinian cohort. Nutrients, 14, 4903. DOI: https://doi.org/10.3390/nu14224903

Melis, M., Mastinu, M., Pintus, S., Cabras, T., Crnjar, R. & Barbarossa, I.T. (2021). Differences in salivary proteins as a function of PROP taster status and gender in normal weight and obese subjects. Molecules, 26, 2244. DOI: https://doi.org/10.3390/molecules26082244

Naciri, L.C., Mastinu, M., Crnjar, R., Barbarossa, I.T. & Melis, M. (2023). Automated identification of the genetic variants of TAS2R38 bitter taste receptor with supervised learning. Computational and Structural Biotechnology Journal, 21, 1054-1065. DOI: https://doi.org/10.1016/j.csbj.2023.01.029

Rangel-Villalobos, H., Muñoz-Valle, J.F.; González-Martín, A., Gorostiza, A., Magaña, M.T. & Páez-Riveros, L.A. (2008). Genetic admixture, relatedness, and structure patterns among Mexican populations revealed by the Y-chromosome. American Journal of Physical Anthropology. 135, 448-461. DOI: https://doi.org/10.1002/ajpa.20765

Risso, D.S., Kozlitina, J., Sainz, E., Gutierrez, J., Wooding, S., Getachew, B., Luiselli, D., Berg, C.J. & Drayna, D. 2016. Genetic variation in the TAS2R38 bitter taste receptor and smoking behaviors. PLoS ONE, 11(10), e0164157. DOI: https://doi.org/10.1371/journal.pone.0164157

Robino, A., Mezzavilla, M., Pirastu, N., Dognini, M., Tepper, B.J. & Gasparini, P. (2014). A population-based approach to study the impact of PROP perception on food liking in populations along the Silk Road. PLoS ONE. 9 (3), e91716. DOI: https://doi.org/10.1371/journal.pone.0091716

Tepper, B.J., Christensen, C.M. & Cao, J. (2001). Development of brief methods to classify individuals by PROP taster status. Physiology and Behavior. 73(4), 571-577. DOI: https://doi.org/10.1016/S0031-9384(01)00500-5

Tepper, B.J.; White, E.A.; Koelliker, Y.; Lanzara, C.; d´Adamo, P. & Gasparini, P. (2009). Genetic variation in taste sensitivity to 6-n-propylthiouracil and its relationship to taste perception and food selection. Annals of the New York Academy of Sciences. 1170, 126.139. DOI: https://doi.org/10.1111/j.1749-6632.2009.03916.x

Trius-Soler, M.; Bersano-Reyes, P.A.; Góngora, C.; Lamuela-Raventós, R.M.; Nieto, G & Moreno, J.J. (2022). Association of phenylthiocarbamide perception with anthropometric variables and intake and liking for bitter vegetables. Genes & Nutrition. 17(1), 12. DOI: https://doi.org/10.1186/s12263-022-00715-w

Wang, X., Wang, L., Xia, M., Teng, F., Chen, X., Huang, R., Zhou, J., Xiao, J. & Zhai, L. (2022). Variations in the TAS2R38 gene among college students in Hubei. Hereditas, 159(1), 46. DOI: https://doi.org/10.1186/s41065-022-00260-x

Wilkerson, J.E.; Bailey, J.M.; Bieniasz, M.E.; Rock, C.L. & Ruffin, M.T. (2008). Cervical cancer precursors, diet and bitter taste (6-n-propylthiouracil `PROP´) receptors. The Open Nutrition Journal. 2, 51-53. DOI: https://doi.org/10.2174/1874288200802010051

Yackinous, C.A. & Guinard, J.-X. (2002). Relation between PROP (6-n-propylthiouracil) taster status, taste anatomy and dietary intake measures for young men and women. Appetite. 38,201-209. DOI: https://doi.org/10.1006/appe.2001.0481

Zhao, L. & Tepper, B.J. (2007). Perception and acceptance of selected high-intensity sweeteners and blends in model soft drinks by propylthiouracil (PROP) non-tasters and super-tasters. Food Quality and Preference. 18, 531-540. DOI: https://doi.org/10.1016/j.foodqual.2006.07.004

Published

2024-03-19

How to Cite

Barajas-Ramírez, J. A., Aguilar-Raymundo, V. G., León-Medina, M. M., & Sánchez-Gutiérrez, M. E. (2024). Análisis de la sensibilidad gustativa al estímulo amargo en dos poblaciones mexicanas. Revista Investigación Y Desarrollo En Ciencia Y Tecnología De Alimentos, 9(1), 23–31. https://doi.org/10.29105/idcyta.v9i1.127